Multilayer Nanoencapsulation

                   ----------  New Approach for Immune Protection of Human Pancreatic Islets

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(1) de Haan, B. J.; Faas, M. M.; de Vos, P. Factors Influencing Insulin Secretion From Encapsulated Islets. Cell Transplant. 2003, 12, 617- 625.
(2) De Vos, P.; Marchetti, P. Encapsulation of pancreatic islets for transplantation in diabetes, the untouchable islets. Trends Mol. Med. 2002, 8, 363-366.
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(4) De Groot, M.; Keizer, P. P.; De Haan, B. J.; Schuurs, T. A.; Leuvenink, H. G.; et al. Microcapsules and their ability to protect islets against cytokine-mediated dysfunction. Transplant. Proc. 2001, 33, 1711-1712.
(5) Zimmermann, U.; Thurmer, F.; Jork, A.; Weber, M.; Mimietz, S.; etal. A novel class of amitogenic alginate microcapsules for long-term immunoisolated transplantation. Ann. N. Y. Acad. Sci. 2001, 944, 199-215.
(6) Klueh, U.; Dorsky, D. I.; Kreutzer, D. L. Enhancement of implantable glucose sensor function in vivo using gene transfer-induced neovascularization. Biomaterials 2005, 26 1155-1163.
(7) Schneider, Stephan, Feilen, Peter J., Kraus, Oliver, Haase, Tanja; et al. Biocompatibility of Alginates for Grafting: Impact of Alginate Molecular Weight. Artif. Cells, Blood Substitutes, Biotechnol. 2003, 31, 383-394.
(8) Elbert, D. L.; Herbert, C. B.; Hubbell, J. A. Thin polymer layers formed by polyelectrolyte multilayer techniques on biological surfaces. Langmuir 1999, 15, 5355-5362.
(9) De Rosa, M.; Carteni, M.; Petillo, O.; Calarco, A.; Margarucci, S.; et al. Cationic Polyelectrolyte Hydrogel Fosters Fibroblast Spreading Proliferation and Extracellular Matrix Production, Implications for Tissue Engineering. J. Cell. Phys. 2004, 198, 133-143.
(10) Schneider, S.; Feilen, P. J.; Slotty, V.; Kampfner, D.; Preuss, S.; et al. Multilayer capsules, a promising microencapsulation system for transplantation of pancreatic islets. Biomaterials 2001, 22, 1961- 1970.

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BME 240

Designed by Shan Yang
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