---------- New Approach for Immune Protection of Human Pancreatic Islets
What is Diabetes?
Diabetes is a disease that affects human body¨s ability to produce or use insulin which helps transport energy (glucose) from food to cells.
Diabetes Mellitus (Type I)
- body cannot produce insulin
- Non-Insulin Dependent
- Due to a combination of defective insulin secretion and defective responsiveness to insulin
Where does insulin come from?
There is only one organ in human body which could secrete insulin-------- It is PANCREAS!
1)Exocrine: Produces digestive enzymes
2)Endocrine: Produce hormones including insulin
Normal Pancreas Tissue Structure and Function
Beta Cells: Secrete Insulin
All Beta cells are included in islets of pancreas .
Function of Insulin
mediates signal transduction pathway to allow GLUT4 receptor to uptake glucose.
Without Insulin, glucose accumulates in the blood stream leading to toxic effects
A Promising treatment for Diabetes
Multilayer Nanoencapsulation of Human Pancreatic Islets using for islet transplantation
Designed by Shan Yang