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Neuronal Regeneration


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Anatomy and Physiology

Neuronal  Regerneration:  Different Approaches

Neuronal  Regerneration:  Mechanism

References





  Axonal damage is critical to the etiology of CNS injuries and neurodegenerative diseases (spinal cord injury, Alzheimer disease). Efforts focus on the molecular and cellular mechanisms that influence axonal plasticity and response to injury.

> Investigation of axonal biology in the central nervous system (CNS) is hindered by lack of an appropriate in vitro method to separate axons independently from cell bodies.

   Control over neuronal growth is a fundamental objective in biophysics, neuroscience, cell biology and biomedicine and is most important for the formation of neural circuits in vitro, as well as nerve regeneration in vivo.

 Only small random neuronal networks have been built in contact with semiconductor structures because damaging tensions rip apart neuronal structures formed on the substrate.

   Understanding how nerves regenerate is an important step towards developing treatments for human neurological disease.

   Knowledge of axonal injury and regeneration thereafter is critical to the etiology of CNS injuries and neurodegenerative disease (for example, spinal cord injury and Alzheimer disease); therefore, considerable effort focuses on the molecular and cellular mechanisms that influence axonal plasticity and response to injury.

 In the case of endogenous or exogenous nerve injury, medication for the blood disease or injury is the only useful treatment. However, the patient occasionally has a functional disability as a sequela. Regeneration of injured nerves and recovery of function is desired. Hence regeneration of the central nervous system is very important.

  Future ability to regenerate the retinal neurons to treat various eye disorders.


UCI BME                                                                                Khyati Mohanty                                                           BME 240