ANATOMY  & PHYSIOLOGY



NERVOUS SYSTEM: (Marieb et.al.)

The Nervous System has three overlapping functions:

*      Sensory receptors monitor changes inside and outside the body
                     §   Change – a stimulus
                     §   Gathered information – sensory input
*      CNS Processes and interprets sensory input
                      §   Makes decisions – integration
*      Dictates a response by activating effector organs
                      §   Response – motor output
*      Cells are densely packed and intertwined  and has two main cell types
                      §    Neurons – transmit electrical signals
                      §    Support cells (neuroglial cells) – non-excitable, surround & wrap neurons

Neuron:
Ø      basic structural unit of the nervous system
Ø      conduct electrical impulses along the plasma membrane – graded and action potential.
Ø      can live and function for a lifetime
Ø    does not divide – fetal neurons lose their ability to undergo mitosis; neural stem cells are an exception
Ø      high metabolic rate – require abundant oxygen and glucose

Axons (nerve fibers)

•         Neuron has only one axon, but it can branch
•         Impulse generator and conductor
•         Transmits action potentials away from the cell body
•         Chromatophilic bodies absent
•         No protein synthesis in axon

Neurofilaments, actin microfilaments, and microtubules
•         Provide strength along length of axon
•         Aid in the transport of substances to and from the cell body
•         Axonal transport

Dendrites
•         Extensively branching from the cell body
•         Transmit electrical signals (graded potentials) toward the cell body
•         Chromatophilic bodies – only extend into the basal part of dendrites
Function as receptive sites