Magnetic iron oxide nanoparticles
for MR contrast agents


Why magnetic nanoparticles?
- Superparamagnetism

How SPIO works as MRI contrast agents?

Commercialized SPIO MRI contrast agents

In vivo detection of biological targets



Magnetic resonance imaging (MRI) applications have steadily widened over the past decade. Currently, it is the preferred cross-sectional imaging modality in most diseases of the brain, spine and musculoskeletal system, providing non-invasive nature and multi-dimensional tomographic capabilities coupled with high-spatial resolution.

Generally, contrast agents are introduced to the anatomical or functional region being imaged, to increase the differences between different tissues or between normal and abnormal tissue, by altering the relaxation times. Magnetic nanoparticles provide strong contrast effects on surrounding tissues under MRI scans and therefore have served as important probes for MR imaging.

This site is intended to provide a basic understanding of magnetic properties of iron oxide nanoparticles and their application to MR contrast agents.



created by Yoon Kyung Kim

Clinical Medicine: