Magnetic iron oxide nanoparticles
for MR contrast agents

Introduction

Why magnetic nanoparticles?
- Superparamagnetism

How SPIO works as MRI contrast agents?

Commercialized SPIO MRI contrast agents

In vivo detection of biological targets

References

References

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[3].    Cheon, J. et al., J. Am. Chem. Soc. 127, 12387-12391 (2005)

[4].    Lu, A.-H., Salabas, E.L. & Schüth, F. Angewandte Chemie 46, 1222-1244 (2007)

[5].    Mornet, S. Vesseur, S., Grasset, F. & Duguet, E. J. Mater. Chem. 14, 2161-2175 (2004)

[6].    Weissleder, R. et al., Nature Medicine 6, 351-354 (2000)

[7].    Dzik-Jurasz, A.S.K. British J. Radiology 76, S98-S109 (2003)

[8].    Tanimoto, A. & Kuribayashi, S. European J. Radiology 58, 200-216 (2006)

[9].    http://www.mr-tip.com/serv1.php?type=db

created by Yoon Kyung Kim

Clinical Medicine: BME240