Barrett's Esophagus-2


Esophagus: General
Esophagus: Structure
Esophagus: Function
Barrett's Esophagus-1
Barrett's Esophagus-2
Barrett's Esophagus-3
Photodynamic Therapy




Two criteria are required for the diagnosis of Barrett esophagus: endoscopic evidence of columnar epithelium above the gastroesophageal junction and histologic evidence of intestinal metaplasia in the biopsy specimens from the columnar epithelium (6).  Grossly, Barrett esophagus is recognized as a red, velvety mucosa located between the smooth pale pink esophageal mucosa and the light brown gastric mucosa.  It may exist in tongues or patches extending from the gastroesophaeal junction or as a broad irregular circumferential band displacing the squamoucolumnar junction several centimeters cephalad.  Microscopically, in Barrett esophagus the esophageal squamous epithelium is replaced by metaplastic columnar epithelium containing intestinal goblet cells. 






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