Scaffold properties should be specific to enable cell penetration and tissue formation.
Ideal scaffold for tissue engineering should have the following characteristics:
- Three dimensional and highly porous for cell growth
- Biocompatible with controllable degradation rate
- Suitable surface chemistry for cell attachment
- Mechanical property matched of the tissue
There are limited options available for tissue engineering intestine. The three groups that worked on developing scaffolds are presented in the table below:
Group Name |
The property of scaffold |
Vacanti et al. |
Biodegrable polymer tube with PGA fibers and sprayed outer surface with PLLA. For more info. click here.
|
Conley Wake et al. |
Pliable biodegradable polymer with PLGA and PEG blends with solvent casting. For more info. click here. |
Shimizu et al. |
Collagen sponge from porcine skin reinforced with PLGA. For more info. click here.
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