The DNA Microarray:

        Approaching Personalized Medicine

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Leukemia Research    Studying AML    Studying B-CLL

 

Exploring the potential of personalized treatment of leukemia through microarray assisted gene expression profiling.  

Leukemia is a cancer of the blood.  The four most common forms of Leukemia are:

  • chronic lymphocytic leukemia (CLL)
  • chronic myeloid leukemia (CML)
  • acute lymphocytic leukemia (ALL)
  • acute myeloid leukemia (AML)

Additional information can be found through The NIH on-line Medical Encyclopedia.

The treatment of leukemia is complicated by the heterogynous characteristics and progression of the disease from patient to patient.  To that end gene expression profiling has been actively researched.  In the links above, a number of studies are highlighted to exhibit the potential of this technique.  The studies represent only a fraction of the current research in this field.

For further reading please consult the following scholarly review:

Dunphy, Cherie H. MD, Gene Expression Profiling Data in Lymphoma and Leukemia: Review of the Literature and Extrapolation of Pertinent Clinical Applications, Arch Pathol Lab Med - Vol 130, April 2006

 

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