Achieving a Closed-Loop Artificial Pancreas

Home Clinical Background Current Approaches Design Criteria References

by Kameel Abi-Samra (BME 240, Spring 2009, UC Irvine)



Literature References:

  • Abalovich, A."Pig Pancreatic Islet Transplantation Into Spontaneously Diabetic Dogs" Transplantation Proceedings, 2009, Proc.41, 328-330

  • Kovatchev, Boris P. "A Proof of Concept in Closed-Loop Control of Type 1 Diabetes". Journal of Diabetes Science Technology (2009). 3(1) 44-55.

  • Saudek, D. Christopher "Can Diabetes Be Cured?: Potential Biological and Mechanical Approaches" JAMA, April 15, 2009 -Vol 301. No. 15

  • Shapiro AM, et al. "International trial of the Edmonton protocol for islet transplantation". New England Journal of Medicine. 2006; 355(13) 138-1330

  • Valdez-Gonzalez, Rafael A. "Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study" European Journal of Endocrinology (2005) 153 419427.

  • Ravaine, Valerie. "Chemically Controlled closed-loop insulin delivery". Journal of Controlled Release 132 (2008) 2-11.

  • Weinzimer, Steil "Fully Automated Cloosed-loop" insulin delivery vs. semiautomated hybrid control in pediatric patients with type 1 diabetes using an artifical pancreas". Diabetes Care. 2008. 31(5). 934-939.


Website References: