The DNA Microarray:

        Approaching Personalized Medicine

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Information for this website was gathered from the following sources:

Muller, U. R & Nicolau, D. V. (Eds), 2005, Microarray Technology and Its Applications, Germany, Springer-Verlag Berlin Heidelberg.

Stathopoulou, F. T.  (Eds), 2005, Genome and Proteome in Oncology, USA, Nova Science Publishers, Inc.

McLachlan, G. J., Do, K., & Ambroise, C., 2004, Analyzing Microarray Gene Expression Data, USA, John Wiley & Sons, Inc.

Okutsu, J et al., 2002, Prediction of Chemosensitivity for Patients with Acute Myeloid Leukemia, According to Expression Levels of 28 Genes Selected by Genome-wide Complementary DNA Microarray Analysis, Molecular Cancer Therapeutics, Vol 1, 1035-1042 Oct 2002.

Valk, P. J. et al, 2004, Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia, The New England Journal of Medicine, 350;16 April 15, 2004.

Grimwade, D. & Haferlach, T., 2004, Gene-Expression Profiling in Acute Myeloid Leukemia (Editorial), The New England Journal of Medicine, 350;16 April 15, 2004.

Ramaswamy, S. & Golub, T., 2001, DNA Microarrays in Clinical Oncology, Journal of Clinical Oncology, Vol 20, No 7 April 2002.

Margalit, O. et al., 2005, Microarray-based gene expression profiling of hematologic malignancies: basic concepts and clinical applications, Blood Reviews, Vol 19 Issue 4.

Schroers, R. et al., 2005, Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia, Leukemia, 19, 750-758 2005.

Schwaenen, C. et al., 2004, Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations,  PNAS, vol 101 no 4 1039-1044.

Kemp, D. & Habener, J., 2004, Functional Genomics in the Clinic: A path Toward Personalized Medicine (Commentary), Preclinica, Vol. 2, No. 6, November/December 2004.

Heller, R. et al., 1997, Discovery and analysis of inflammatory disease-related genes using cDNA microarrays, Proc. Natl. Acad. Sci, Vol. 94, pp2150-2155, March 1997.

 

Un-cited photographs were pulled from the following websites:

www.npaci.edu/online/v4.12/pettitt.html
www.virogenomics.com/news_microarray.htm

www.lshtm.ac.uk/itd/grf/microarrayoverview.htm
MedlinePlus- NIH online medical Encyclopedia

 

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Site creator: Fred Ayers