Magnetic iron oxide nanoparticles
for MR contrast agents


Introduction

Why magnetic nanoparticles?
- Superparamagnetism

How SPIO works as MRI contrast agents?

Commercialized SPIO MRI contrast agents

In vivo detection of biological targets

References

References

[1].    Jun, Y.-W., Seo, J.-W. & Cheon, J. Accounts of Chemical Research 2, 179-189 (2008)

[2].    Jun, Y.-W., Jang, J.-T. & Cheon, J. Bull. Korean Chem. Soc. 27, 961-971 (2006)

[3].    Cheon, J. et al., J. Am. Chem. Soc. 127, 12387-12391 (2005)

[4].    Lu, A.-H., Salabas, E.L. & Schüth, F. Angewandte Chemie 46, 1222-1244 (2007)

[5].    Mornet, S. Vesseur, S., Grasset, F. & Duguet, E. J. Mater. Chem. 14, 2161-2175 (2004)

[6].    Weissleder, R. et al., Nature Medicine 6, 351-354 (2000)

[7].    Dzik-Jurasz, A.S.K. British J. Radiology 76, S98-S109 (2003)

[8].    Tanimoto, A. & Kuribayashi, S. European J. Radiology 58, 200-216 (2006)

[9].    http://www.mr-tip.com/serv1.php?type=db

 

created by Yoon Kyung Kim

Clinical Medicine:
BME240